Adiponectin is a special hormone that plays a crucial role in regulating blood glucose levels and fatty acid breakdown. When people become fat, the production of Adiponectin slows down or shutdown, setting them up for disease. High levels of Adiponectin in the blood are associated with a reduced risk of heart attack. Adiponectin also has an anti-inflammatory effect on the cells lining walls of blood vessels. When Adiponectin levels are low, your body can accumulate unhealthy fat, and insulin resistance may take place. People with low levels of Adiponectin are obese and are at increase risk of cardiovascular disease. You Need Adiponectin to lose weight and the best source of adiponectin is Ashitaba